Diabetes

The internet has so many people jumping on different products with bogus health claims making them look like pixie dust.

Apple cider vinegar is one of such products with so many purported health benefits. Now this doesn’t mean that apple cider vinegar is pixie dust or adder poison

Apple cider vinegar has some proven benefits and we’ll look into those benefits and limitations in this write up.

How Apple Cider Vinegar Is Made
Vinegar comes from a French word ‘vin aigre’, meaning sour wine. Apple cider vinegar is gotten from a process of ‘controlled spoilage’.

The sugars in apple is digested by yeast thereby converting it into alcohol. Then a bacteria, acetobacter converts the alcohol into acetic acid which gives it a sour taste.

The combination of yeast and bacteria (mother) acts as a probiotic.
The profile of apple cider vinegar which contains probiotics, acetic acid and other nutrients surely provides certain health benefits to the consumer:

CLAIMS
1. Apple cider may help with blood sugar control: the exact mechanism behind this is not really known, but some studies suggests suppression of disaccharidase activity, delayed gastric emptying, enhanced glucose uptake in the periphery and conversion to glycogen, and increased satiety. Some studies showed how taking in 20g of apple cider vinegar 30-60mins significantly lowered post pandral glucose levels.

Another study showed that vinegar does not act to decrease glycaemia by interference with enteral carbohydrate absorption.
In all, apple cider vinegar does not cure diabetes and cannot take the place of medication and dietary aides to manage diabetes but can be used alongside medications and diet to help in the management of diabetes.

2. Apple cider may help boost weightloss: some studies suggest that acetic acid can prevent fat deposition and improve metabolism. Taking 1-2 spoons of apple cider vinegar may help in modest weight loss by the mechanism mentioned above.

Studies also showed that participants ate a diet of 250 lesser than their normal daily requirements. Apple cider on its own won’t lead to weight loss, so don’t shove your meal plans and gym routines aside
3. Apple cider helps control blood pressure: no scientific claims to back this up on humans yet
4. Apple cider vinegar will not cure cancer

LIMITATIONS
– It can alter insulin levels thereby possibly leading to hypoglycaemia if taken in high does. Diabetic patients should be aware of this.
– It can damage the tooth enamel due to its high acidity. It should be diluted before consumption
– It might lower potassium levels. People with hypertension who are on diuretics should be careful with usage.

CONCLUSION
Apple cider vinegar is almost like any other over the counter supplement. It won’t replace healthy lifestyle.

SOURCES: 1.https://www.health.harvard.edu/blog/apple-cider-vinegar-diet-does-it-really-work-2018042513703
2. https://pubmed.ncbi.nlm.nih.gov/29091513/
3.https://www.uchicagomedicine.org/forefront/health-and-wellness-articles/debunking-the-health-benefits-of-apple-cider-vinegar

 

IF simply involves switching between fasting and eating on your normal schedule.
This method could help you manage your weight and ward off chronic diseases if monitored and done effectively.

BASIC CONCEPTS
Before going into this practice, it is important to know what it entails.
Some basics to know:
– you have to skip one meal
– you can still have your favourite healthy meal while fasting
– you can drink water while fasting
– you can have no-calorie beverages while fasting. Examples include coffee, green or black tea.

So for everyone that has heard about IF or has practised it before, normally, you would skip breakfast while fasting, because it feels easier.
-But, according to a research carried out by USDA economic research service, it was noticed that skipping dinner, reduced more daily calories and lowered diet quality the least when compared to skipping breakfast or lunch.
-Also note that your night fast should be longer than 2 hours and shorter than 24 hours

TYPES OF IF
There are basically 3 popular types of IF:
– 16:8 method
– 5:2 method
– eat-stop eat method.
Others include OMAD, and warrior diet.

16: 8 METHOD

This method involves restricting your eating to just 8 hours windows in a day. you have to fast for the remaining 16 hours of that day.
– It is the most popular and preferred style
– A 2016 study found that when combined with resistance training, the 16/8 method helped decreased fat mass and maintain muscle mass in male participants.
– A more recent study found that the 16/8 method did not impair gains in muscle or strength in women performing resistance training

5:2 METHOD

This method involves eating normally for 5 days in a week, then restricting your calorie intake to 500 calories for the remaining 2 days.
– According to a 2018 study, the 5:2 diet is just as effective as daily calorie restriction for weight loss and blood glucose control among those with type 2 diabetes.

EAT-STOP-EAT METHOD
This method involves fasting for 24 hours twice or thrice a week.
– Fasting for 24 hours would lead to a metabolic shift and ause your body to use up fat
– But staying off food for 24 hours might lead to binging and overconsumption.

IF AND YOUR HORMONES
– IF positively affects the human growth hormone (HGH), especially when done adequately. These hormone levels increase when you do IF, and higher levels of this hormone facilitate fat burning and muscle gain.
– IF also increases the amount of norepinephrine in our bodies which help to breakdown body fat and facilitate it use for energy
– intermittent fasting decreases androgen markers (i.e., testosterone and the free androgen index (FAI)) while increasing sex hormone-binding globulin (SHBG) levels in premenopausal females with obesity.
– fasting may prove to be a valuable tool for treating hyperandrogenism in females with polycystic ovarian syndrome (PCOS) by improving menstruation and fertility.

BENEFITS
– WEIGHTLOSS: A 2014 review of scientific literature found that IF can cause 3–8% weight loss over 3–24 weeks, which is a significant amount. Also, participants lost 4-7% of their waist circumference.
– CAN REDUCE INSULIN RESISTANCE: IF can help reduce insulin resistance. According to research, it can help reduce blood sugar by 3–6% and fasting insulin levels by 20–31%.
– HEART-HEALTH: IF may help to reduce bad cholesterol, and blood triglycerides.
– OXIDATIVE STRESS: IF may help reduce inflammation (a key factor in disease processes) and oxidative stress.
– BRAIN HEALTH: may increase the brain hormone brain derived neurotrophic factor (BDNF) and may help in the growth of new nerves. it also may help prevent alzemheirs
– DECREASE IN APPETITE: according to research, time-restricted fasting (16 8), decreased mean ghrelin levels, increased fullness in participants, and decrease the desire to eat.
Also, in the first 12 hours of fasting, there is a slight increase in ketone bodies, this helps in appetite suppression.

POSSIBLE DOWNSIDES
– Malnutrition: if not done properly, intermittent fasting could lead to serious malnutrition. some very vital micronutrients and electrolytes might be lacking in your diet if not monitored.
– Dehydration: during a fast, your body tends to release water and salt via the urine. if this water isn’t replenished, you get dehydrated.
– Bad breath: during fasting, fat is used up majorly as fuel. fat metabolism leads to acetone formation which can affect your breath
-fatigue and low energy: when fasting, especially if you are not adequately monitored, with an inadequate intake of calories, you tend to be fatigued due to a low intake of calories
5. Headaches and lightheadedness: this is most common in intermittent fasting and occurs within the first few days especially if you’re a newbie.
6. Hunger and cravings: normally you’d feel hunger cues during your fasting. they tend to be heavier if you don’t do it well.
Most of these side effects should disappear in 2 weeks,

TIPS TO NAVIGATE EFFECTIVELY
• Know your nutrient needs
• Always incorporate proteins into your eating window
• Know your energy requirements
• Always stay hydrated
• Avoid overeating/undereating
• Maintain a balanced diet
• Try out the different types of IF
• Keep track of your journey
• Adapt a suitable workout routine
• Plan meals
• Speak to a registered dietitian

WHO SHOULD NOT BE ON IF?
• If you are underweight
• If you have a history of an eating disorder
• If you are pregnant
• If you are breastfeeding
• If you are on insulin (type 1)
• Anyone with immunosuppression
• Transplant patients
• Chronic kidney diseases
• Poorly controlled diabetes (unless an endocrinologist is involved).
• Adolescents and kids
• Elderly (muscle mass)

SUMMARY
The intermittent fasting pattern of eating is quite a beneficial one with side effects that can easily be managed. But, it is important that you are monitored by health practitioners before delving into this type of diet.
Also, before starting, be sure of the type of fast that would suit your lifetyle and schedule.

SOURCES:
-https://www.hopkinsmedicine.org/health/wellness-and-prevention/intermittent-fasting-what-is-it-and-how-does-it-work
– https://www.healthline.com/nutrition/6-ways-to-do-intermittent-fasting
– https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680567/
– https://pubmed.ncbi.nlm.nih.gov/31525701/

Blood sugar readings can be fickle; and this is regardless of whether you were just diagnosed recently, or you’ve been diagnosed over a long period of time.

Apart from the fact of its fickleness, it is also very important that it is always in check and managed well

Proper blood glucose management can help to prevent you from potential diabetes complications like nerve damage, kidney disease, vision problems, heart diseases and stroke

Learning how different habits and factors can cause blood sugar to fluctuate can help you prepare for, and predict fluctuations

It is important to note that some of these factors are out of control; even though you stick to your medications and diet, your blood sugar will still tend to fluctuate.

But that doesn’t mean it cant be prepared to defend against those fluctuations. Keep reading to see factors that could affect blood sugar and what to do about them.

1. DEHYDRATION: sounds awkward right? Well, being dehydrated and having diabetes are co-related. When your body is short of enough fluid supply, the sugar in the cells tends to be high concentrated and this leads to hyperglycaemia.

To make things worse, high blood glucose leads to excessive urination, which can in turn increase dehydration.

So, if you have been diagnosed with diabetes, it is in your interest to stay hydrated always, especially with water.

• 2. SOME MEDICATIONS AFFECTS BLOOD SUGAR: apart from your oral drugs to help manage diabetes, some other over-the-counter drugs you’re on can alter glucose readings.

Drugs used to treat inflammatory conditions, autoimmune disorders, and asthma can cause a spike in blood glucose.

3. DAWN PHENOMENON: you might have experienced this one time or the other when your blood sugar levels spike at early mornings even if you did so well with your drugs and diet the previous night.

It might just be dawns phenomenon: your body releases cortisol during 2am-8am, and this hormone has a way of making your body less sensitive to insulin.

You should check with your doctor if this continues regularly.

Apart to inadequate management and abuse of oral glycaemic drugs, some other factors might be influencing your blood sugar readings

You have noticed that your crossed all your T’s and dotted all your I’s and still? Just maybe, these factors are involved.

 

SOURCES:
– https://www.everydayhealth.com/type-2-diabetes/symptoms/surprising-causes-of-blood-sugar-swings/
– https://www.cdc.gov/diabetes/library/spotlights/blood-sugar.html
– https://www.mayoclinic.org/diseases-conditions/diabetes/expert-answers/dawn-effect/faq-20057937#:~:text=The%20dawn%20phenomenon%2C%20also%20called,a.m.%20%E2%80%94%20in%20people%20with%20diabetes.
– https://www.ncbi.nlm.nih.gov/books/NBK430893/

It seems like the trend now is fasting, we’ve come a long way in the nutrition space and there has been so many takes on how to lose weight or help with some chronic diseases.
So the question is: will fasting help me lose weight, manage diabetes and other chronic diseases?

Absolutely! It would, but is it sustainable and convenient?
Is it suitable for everyone? What are the merits and demerits of fasting?
These are the questions we’ll love to use this article to answer, but before then;

WHAT IS INTERMITTENT FASTING?
Intermittent fasting, also known as intermittent energy restriction is any schedule for meals that involves a cycle between voluntary fasting and non-fasting periods. It can include an alternate day fasting, periodic fasting or daily time restricted fasting.

Apart from the religious type of fasting, there are 3 main types of intermittent fast:
– 5:2 Diet: this type of fasting involves that you fast for 2 days per week and you’ll be allowed to take 25% of your daily caloric needs, while you eat normally for 5 days.
– Alternate day fasting: you have to skip a day and eat the other day. So, you eat on Monday and skip Tuesday, eat Wednesday and skip Thursday, and it goes om like that. You’re still allowed to just 25% of your normal daily calories per day In this type of regimen.
– Time restricted fasting: this type involves fasting for 8-12 hours of the day and eating during the remaining time frame. For this, you are not restricted to having just 25% of your daily calories. Apart from the above mentioned, there is the warrior diet also.

IS INTERMITTENT FASTING REALLY EFFECTIVE?
A study found that participants consumed 35% fewer calories and lost an average of 7.7 pounds (3.5kg) after alternating between 36 hours of fasting and 12 hours of unlimited eating over 4 weeks. For some studies, there was not any significant weight loss between the fasting group and moderate calorie group
There are quite a number of side effects of intermittent fasting especially when it is abused and they include: extreme hunger pangs, lightheadedness, reduced concentration, fatigue and nausea. All these put together might just make the regimen to be effective only for a short time.
Furthermore, people might tend to eat more than required on days that they are free to eat would result to no weight loss.

CAN I TRY GOING ON AN INTERMITTENT FAST?
For some groups, intermittent fasting is advised at all, you can still achieve your health goal without having to do marathon fasts
If you have diabetes, on routine medication, pregnant or breastfeeding, you should not do intermittent fasting.
You really should not go on a long fast, or skip meals so you would lose weight or manage your blood sugar levels. The caveat is that when your body doesn’t take in any food, obviously calories would be depleted and other nutrients, thereby leading to a decrease in blood sugar, so it is not magical

You can stick to healthy and mindful eating and still achieve perfect glucose levels and still lose weight without any type of side effects, so why go on a regimen with side effects?

SOURCES

https://www.healthline.com/nutrition/intermittent-fasting-guide

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959807/

OVERVIEW
According to recent studies, it has been shown that 64% of people with type 2 diabetes also suffer from hypertension.
This companionship is actually an ungodly one but sadly, in most cases where adequate management is not adhered to, the combo is just inevitable.
Many underlying pathophysiological mechanisms are associated with the duo, with a few seemingly plausible ones like: sodium-fluid retention, insulin resistance in the nitric-oxide pathway and stiffening of arteries.
Diabetes and hypertension are strongly interrelated and always predisposes individuals to other cardiovascular complications like atherosclerosis and arteriosclerosis.
In this article, we would throw light on both diseases, how to manage them, their symptoms and how to prevent one leading to the other.

IDENTIFYING DIABETES?
Diabetes is a complex condition that impairs the body’s ability to metabolize/use blood sugar in the body.
Globally, more than 422 million people are living with the disease. Currently, 1 out of every 17 adults are living with this disease in Nigeria.
Uncontrolled diabetes, either with medication or diet, or a combination of both therapies would lead to other disease complications like stroke and heart diseases.
There are three types of diabetes and they include: type 1 diabetes, type 2 diabetes and gestational diabetes.

• TYPE 1 DIABETES: this is referred to as juvenile diabetes; more common among younger people. It occurs when the body fails to produce insulin. Sadly, people living with this type of diabetes have to stay on insulin for the rest of their lives to stay alive.

• TYPE 2 DIABETES: this is the most common type of diabetes. It affects how the body uses insulin. The cells in the body do not respond to insulin effectively as they would always do in time past before the onset of this type of diabetes.
Less common types of diabetes include monogenic diabetes and cystic fibrosis-related diabetes.

HOW CAN I GET DIABETES?
The risk factors for type 2 diabetes include:
• If you are overweight (when your BMI is above 25 kg/m2)
• If one of your parents or ancestors has diabetes
• having a high-density lipoprotein (HDL) cholesterol level lower than 40 mg/dL or 50 mg/dL
• If there is an occurrence of high blood pressure in your family lineage
• having gestational diabetes or giving birth to a child with a birth weight of more than 9 pounds
• a history of polycystic ovary syndrome (PCOS)
• being of African-American, Native American, Latin American, or Asian-Pacific Islander descent
• being more than 45 years of age
• having a sedentary lifestyle

HOW WILL I KNOW THAT I HAVE DIABETES?
Type 2 diabetes always presents with symptoms and they include:
– excessive hunger
– excessive thirst
– excessive passing of urine; especially in the night time
– blurry vision
– you easily get tired
In some cases, symptoms might not be noticed on time.

Type 2 diabetes can be diagnosed also if an individual’s blood sugar levels are above 70-90 mg/dl. Normally, to test for diabetes, blood samples are needed. But recently, your tears could be used to test for blood glucose levels.

IDENTIFYING BLOOD PRESSURE
Hypertension is a common condition in which there is a long-term force of blood against your artery walls. This could also predispose the individual to other heart health problems.
Previous studies have recorded that hypertension (commonly called) is more prevalent in men than in women.

CAUSES OF HYPERTENSION
There are a number of risk factors which could lead to hypertension and they include:
• Age.
• Family history (hereditary)
• Ethnic background.
• Obesity and being overweight.
• Lack of physical exercise or activity.
• Smoking.
• Alcohol intake.
• Poor diet and high cholesterol.
There are no symptoms noticed with hypertension; reason why it is called the “silent killer”
People usually find out that they have hypertension when a doctor takes their reading with a sphygmomanometer.
An individual would be said to have hypertension if blood pressure levels are above 140/90 mmHg, in severe cases blood pressure levels might get to 180/120mmHg.

RELATIONSHIP BETWEEN HYPERTENSION AND DIABETES
The duo often occurs together and might even share common causes which include:
– Obesity
– Inflammation
– Oxidative stress
– Insulin resistance
As blood glucose accumulates in the body, some vital organs that help to maintain fluid balance are affected. Organs like the kidneys are more affected because they play an important role in making sure there is no fluid retention which leads to high blood pressure.
There are three ways in which high glucose levels in the blood can increase blood pressure:
• The blood vessels lose their ability to stretch.
• The fluid in the body increases, especially if diabetes is already affecting the kidneys.
• Insulin resistance which may involve processes that increase the risk of hypertension.
It is important to note that the duo could pose huge health complications which includes:
1. heart attack or stroke
2. decreased kidney function, progressing to dialysis
3. problems with the blood vessels in the eyes, leading to vision loss
4. peripheral vascular disease

CAN THIS BE PREVENTED?
Yes! Lifestyle factors are very crucial in the management of both diabetes and hypertension.
These lifestyle factors should be adhered to strictly in order to prevent the onset of the duo
1. A HEALTHY DIET: people who already live with diabetes or hypertension should seek advice from their dietitian to help manage their symptoms in order to avoid an escalating situation.
This advice would include:
– eating plenty of fresh fruits and vegetables
– focusing on high-fiber foods, including whole grains
– limiting (not avoiding) the amount of added salt and sugar
– avoiding or limiting unhealthful fats, such as trans fats and
– avoiding the intake of refined carbs.
2. AVOID ALCOHOL AND SODA DRINKS: high alcohol intake increases the risks of developing these diseases. Surprisingly, people always have the mind-set that alcoholic drinks are healthier options when compared to soft drinks. Both are actually not recommended if these diseases are present.
3. STOP SMOKING: smoking tobacco increases the risk of high blood pressure and diabetes. Smoking could lead to poor blood flow and could damage the heart and lungs.
4. MAINTAIN A HEALTHY WEIGHT: losing weight is actually helpful in preventing the onset of diabetes and hypertension. Losing 3-5% of your weight can improve blood sugar readings.
5. BE ACTIVE: at least 150 minutes of intense exercise could help lower blood pressure levels and blood glucose levels as it helps in good blood circulation.
Note that only diet would not help in the management of diabetes and hypertension or the duo. Medications also are important factors in the management.
Also note that herbs, supplements and concoctions won’t help to eradicate this duo but might even pose greater health risks to the individual.

TAKE HOME
High blood pressure and type 2 diabetes often occur together and tend to share same risk factors.
It’s very important to pay attention to lifestyle modifications if you are living with both diseases or just one of them.
In the management, it’s important to have a doctor and dietitian co-manage your symptoms as diet and medication play a huge role in the management of these diseases.

1. SOURCES: https://www.medicalnewstoday.com/articles/317220#outlook
   https://www.webmd.com/diabetes/high-blood-pressure#:~:text=Diabetes%20damages%20arteries%20and%20makes,heart%20attack%2C%20and%20kidney%20failure.
   https://www.tandfonline.com/doi/abs/10.1080/20786204.2004.10873136

 

OVERVIEW
Allulose is just like the new kid on the block.
Ever looked for healthy alternatives to sugar? Maybe you should give this a try.
Allulose is purported to have similar taste with refined white sugar, but contains minimal amount of calories and carbs when compared to sugar. It also claims to possess some health benefits.
Lets see with this write up the claims of allulose and how safe it is for consumption.

WHAT IS ALLULOSE
Allulose is a monosaccharide as glucose and fructose called D-psicose. It is in contrast to table sugar which has a combination of glucose and fructose.
In fact, fructose has the same chemical structure as allulose but they are arranged differently. This arrangement makes it possible for the body to metabolize allulose in a different manner from fructose.
It’s very rare and can only be found in some foods like figs, raisins, and wheat.
Nutritionally, allulose contains approximately 0.2 kcal/g, which should be about 5% of the calories of sugar. Allulose is absorbed in the small intestine without going through any type of metabolism. So, it goes out through the urine unchanged.
This phenomenon makes it possible for allulose to resist fermentation by the gut bacteria thereby avoiding bloating, and other gas related digestive problems.
There are some health benefits tied to using allulose and they include:

1. IT MIGHT BE USEFUL FOR DIABETICS: due ti its chemical structure, the body tends to metabolise allulose differently thereby leading to an insignificant raise in blood sugar.
According to a recent study, about 7.5g of allulose didn’t impact glucose levels in individuals used for the test.

2. CONTAINS LITTLE AMOUNT OF CALORIES: allulose is a very low calorie containing substance and can be used as sweetener by weight watchers. Allulose contains about 1/10th of sugars calories.

3. IT MAY PROTECT AGAINST FATTY LIVER DISEASE: since allulose is not stored in the body and converted to fat in the liver as fructose, its ability makes it possible for the liver to stay healthy.
Diabetes and insulin insensitivity has been linked to fatty liver diseases recently, with the use of allulose as substitute, the incidence of these might be reduced.
Research also suggests that allulose enhances fat oxidation.
Also, allulose could be used in baking and making of ice-cream as it has similar properties and feels like refined white sugar.

IS ALLULOSE SAFE?
The Food and Drug Administration has added allulose to the list of foods generally recognised as safe (GRAS). It is very rare in markets and not accepted in Europe yet.,
You can get it online but at a very expensive price.

SOURCES:

What is Allulose?

https://www.healthline.com/nutrition/allulose#TOC_TITLE_HDR_5
https://www.todaysdietitian.com/newarchives/0119p32.shtml#:~:text=Allulose%2C%20a%20monosaccharide%2C%20is%20present,%2C%20beets%2C%20or%20other%20sources.

Does Body Weight Affect Cancer Risk?

Being overweight, obese or having a BMI over 30kgmsq (since the society wants to scrap out the word obese) seems to be  linked to an overall increased risk of cancer. According to research from the American Cancer Society, excess body weight is thought to be responsible for about 11% of cancers in women and about 5% of cancers in men in the United States, as well as about 7% of all cancer deaths.  

Being overweight or obese is clearly linked with an increased risk of 13 types of cancer, which includes:

• Breast cancer (in women past menopause)
• Colon and rectal cancer (diet related)
• Endometrial cancer (cancer of the lining of the uterus)
• Esophagus cancer (diet related)
• Gallbladder cancer (diet related)
• Kidney cancer (diet related)
• Liver cancer (diet related)
• Ovarian cancer
• Pancreas cancer (diet related)
• Stomach cancer (diet related)
• Thyroid cancer (diet related)
• Multiple myeloma
• Meningioma (a tumor of the lining of the brain and spinal cord). Notice that there is a correlation with diet and almost 80% of all stated cancers. Most part of your body more vulnerable to cancers are the ones exposed to whatever dietary choices you make.

Being overweight or obese might also raise the risk of other cancers, such as:

• Non-Hodgkin lymphoma
• Male breast cancer
• Cancers of the mouth, throat, and voice box
• Aggressive forms of prostate cancer

The bond between cancer and  body weight is stronger for some cancers than for others. For example, excess body weight is thought to be a factor in more than half of all endometrial cancers, whereas it is linked to a smaller portion of other cancers.

Understanding the link between body weight and cancers is quite complex and might tip you off balance a bit. For example, while studies have found that excess weight is linked with an increased risk of breast cancer in women after menopause, it does not seem to increase the risk of breast cancer before menopause. Reasons best known to science (giggles).

The time of an individual’s life in which they gain weight might also affect cancer risk. Being overweight during childhood and young adulthood might be more of a risk factor than gaining weight later in life for some cancers. For example, some research suggests that women who are overweight as teenagers (but not those who gain weight as adults) may be at higher risk for developing ovarian cancer before menopause.

More research still needs to be carried out to back up some of these claims 

 

How might body weight affect cancer risk?

Excess body weight may affect cancer risk in a number of ways, some of which might be specific to certain cancer types. Excess body fat might increase cancer risk by affecting:

• Inflammation in the body
• Cell and blood vessel growth
• Cells’ ability to live longer than they normally would
• Levels of certain hormones, such as insulin and estrogen, which can fuel cell growth
• Other factors that regulate cell growth, such as insulin-like growth factor-1 (IGF-1)
• The ability of cancer cells to spread (metastasize)

Does losing weight reduce cancer risk?

Research on how losing weight might lower the risk of developing cancer is limited. Still, there’s growing evidence that weight loss might reduce the risk of some types of cancer, such as breast cancer (after menopause) and endometrial cancer.

Some body changes that occur as a result of weight loss suggest it may, indeed, reduce cancer risk. For example, overweight or obese people who intentionally lose weight have reduced levels of certain hormones that are related to cancer risk, such as insulin, estrogens, and androgens.

While we still have much to learn about the link between weight loss and cancer risk, people who are overweight or obese should be encouraged and supported if they try to lose weight. Aside from possibly reducing cancer risk, losing weight can have many other health benefits, such as lowering the risk of heart disease and diabetes. Losing even a small amount of weight has health benefits and is a good place to start.

It’s important to lose body weight, but much more important to lose body fat rather than just water fat (glycogen stores). So rather than cutting out carbs with chain saws and axes, reduce the amount of trans fat and ensure you take in quality nutrients. 

 

The science around it all

Overall, the majority of hypotheses proposed over the past 20–30 years have been based around the physiological functions and pathological correlations of compounds intimately involved in general metabolism of adipose tissue or its regulation by systemic factors and the relevance of those compounds to cell proliferation or development that could contribute to abnormal proliferation and migration leading to oncogenesis (development of tumors). The more recently developed concepts to be described below adopt a wider perspective in which the interface between adipose metabolism, inflammation and carcinogenesis is mediated by newly uncovered links involving biochemical pathways which open new perspectives on the obesity/cancer relationship in a more holistic, biologically integrated manner.

 These ideas include the inflammation-induced activation of the kynurenine pathway and its role in feeding and metabolism by activation of the aryl hydrocarbon receptor (AHR) and by modulating synaptic transmission in the brain. Evidence for a role of the kynurenine pathway in carcinogenesis then provides a potentially major link between obesity and cancer. A second new hypothesis is based on evidence that serine proteases can deplete cells of the tumour suppressors Deleted in Colorectal Cancer (DCC) and neogenin. These enzymes include mammalian chymotryptic proteases released by pro-inflammatory neutrophils and macrophages.

The kynurenine pathway represents the dominant pathway of tryptophan catabolism, accounting for the disposal of around 95% of the tryptophan not used for protein synthesis.

According to a research carried out by Jin in 2015, he stated and i quote that “the relevance of the kynurenine pathway is that not only do its components affect the regulation of metabolism, feeding and body mass, largely via the modulation of NMDA receptor activity, but they are also implicated in aspects of carcinogenesis’. Expression of the central enzyme of the pathway – kynurenine-3-monooxygenase (KMO) is greater in human hepatic carcinoma cells than controls and is known to influence cell proliferation and migration.

Other factors like insulin resistance, high glucagon and leptin levels (in obese and diabetic patients), adipokines (adiponectin) which is reduced in obese patients, highly concentrated levels of ceruloplasmin in adipose tissues of obese patients, might also increase an obese patients risk to several types of cancer. 

 

Dietary consideration 

Bowman-Birk inhibitors are relatively small proteins found in plant based foods, highly stable within the intestine and generally resistant to heating and cooking, which are known to be absorbed from the intestine into the blood. 

Several studies suggest that the presence of bowman’s birk inhibitors (BBI) are capable of inducing apoptosis in human breast carcinoma. The BBI is also capable of suppressing carcinogenic processes that include colon, oral leukoplakia, esophageal tumors, leukemia, prostatic hyperplasia and breast cancer (quite elusive though).

An overall healthy diet and lifestyle cannot be over emphasized, whether you choose a ‘only plant based diet’ or you choose to do a variety, make sure you do the right thing for your body MODERATION! 

 

Sources: https://www.nature.com/articles/cddiscovery201567

https://www.cancer.org/cancer/cancer-causes/diet-physical-activity/body-weight-and-cancer-risk/effects.html

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952217/

 

It’s no news that the amount of calories people eat and drink has a direct effect on their weight: Calories in = Calories out, and weight stays stable. Calories in > Calories out , weight goes up. Less calories in, and well, weight goes down.

 But what about the type of calories: Does it matter if they come from specific nutrients-fat, protein, or carbohydrate? Specific foods-whole grains or pop-corn? Specific diets-the Mediterranean diet or the “Keto” diet? And what about when or where people consume their calories: Does eating breakfast make it easier to control weight? Does eating at fast-food restaurants make it harder?

There’s ample research on foods and diet patterns that protect against heart disease, stroke, diabetes, and other chronic conditions. The good news is that many of the foods that help prevent disease also seem to help with weight control-foods like whole grains, vegetables, fruits, and nuts. And many of the foods that increase disease risk-chief among them, refined grains and sugary drinks-are also factors in weight gain. Conventional wisdom says that since a calorie is a calorie, regardless of its source, the best advice for weight control is simply to eat less and exercise more. Yet emerging research suggests that some foods and eating patterns may make it easier to keep calories in check, while others may make people more likely to overeat.

 

Let’s briefly review the research on dietary intake and weight control, highlighting diet strategies that also help prevent chronic disease.

 

 

• Macronutrients and Weight: Do Carbs, Protein, or Fat Matter?

 

It really looks like the percentage of calories from carbs, fats or proteins do not really contribute to weight gain. So, the quantity of macronutrients you consume per day might not be directly proportional to the weight you add-on. In saner climes, there may be some benefits to a higher protein, lower carbohydrate approach, or even a high fat, low carb approach. For chronic disease prevention, though, the quality and food sources of these nutrients matters more than their relative quantity in the diet. And the latest research suggests that the same diet quality message applies for weight control.

 

• Dietary Fat and Weight

 

Low-fat diets have long been touted as the key to a healthy weight and to good health. But the evidence just isn’t there: Over the past  years globally and especially in western countries, the percentage of calories from fat in people’s diets has gone down, but obesity rates have skyrocketed.  “Carefully conducted clinical trials have found that following a low-fat diet does not make it any easier to lose weight than following a moderate- or high-fat diet”. In fact, study volunteers who follow moderate- or high-fat diets lose just as much weight, and in some studies a bit more, as those who follow low-fat diets. And when it comes to disease prevention, low-fat diets don’t really appear to offer any special benefits except in very strict conditions. 

“Part of the problem with low-fat diets is that they are often high in carbohydrates, especially from rapidly digested sources, such as white bread and white rice. And diets high in such foods might further increase the risk of weight gain, diabetes, and heart disease”.

For good health, the type (in terms of quality) of fat people eat is far more important than the amount , and there’s some evidence that the same may be true for weight control. Studies have shown clearly that over consumption of trans fat and saturated fats would lead to heart and possibly other non-communicable diseases, but not the same with monounsaturated and polyunsaturated fatty acids which offer health benefits.

 

• Protein and Weight

 

Although  high-protein diets seem to perform equally well as other types of diets, they still tend to be low in carbohydrate and high in fat or sometimes vice versa as the case may be, so it is difficult to tease apart the benefits of eating lots of protein from those of eating more fat or less carbohydrate. But there are a few reasons why eating a higher percentage of calories from protein may help with weight control:

• More satiety: People tend to feel fuller, on fewer calories, after eating protein than they do after eating carbohydrate or fat.
• Greater thermic effect: It takes more energy to metabolize and store protein than other macronutrients, and this may help people increase the energy they burn each day. About 30-35% is metabolised almost immediately.
• Improved body composition: Protein seems to help people hang on to lean muscle during weight loss, and this, too, can help boost the energy-burned side of the energy balance equation. 

“Higher protein, lower carbohydrate diets improve blood lipid profiles and other metabolic markers, so they may help prevent heart disease and diabetes”. But some high-protein foods are healthier than others: High and uncontrolled intakes of red meat and processed meat are associated with an increased risk of heart disease, diabetes, and colon cancer.

Replacing red processed meat with nuts, beans, fish, or poultry seems to lower the risk of heart disease and diabetes.  And this diet strategy may help with weight control, too, according to a recent study from the Harvard School of Public Health.

 

• Carbohydrates and Weight

 

Lower carbohydrate, higher protein or even lower carbs, moderate protein and high fat diets may have some weight loss advantages in the short term.  Yet when it comes to preventing weight gain and chronic disease, carbohydrate quality is much more important than carbohydrate quantity.

‘Milled, refined grains and the foods made with them-white rice, white bread, white pasta, processed breakfast cereals, and the like-are rich in rapidly digested carbohydrates. So are potatoes and sugary drinks. The scientific term for this is that they have a high glycemic index and glycemic load. “Such foods cause fast and furious increases in blood sugar and insulin that, in the short term, can cause hunger to spike and can lead to overeating-and over the long term, increase the risk of weight gain, diabetes, and heart disease”. 

Are there Specific Foods that Make It Easier or Harder to Control Weight?

There’s growing evidence that specific food choices may help with weight control, but does not suggest that one food will help in weight loss or gain (super food). The good news is that many of the foods that are beneficial for weight control also help prevent heart disease, diabetes, and other chronic diseases. There are a number of foods and drinks that contribute to weight gain—chief among them, refined grains and sugary drinks—also contribute to chronic disease.

 

• Whole Grains, Fruits and Vegetables, and Weight

 

Whole grains-whole wheat, brown rice, barley, and the like, especially in their less-processed forms-are digested more slowly than refined grains. So they have a gentler effect on blood sugar and insulin, which MAYhelp keep hunger at bay. The same is true for most vegetables and fruits. These “slow carb” foods have bountiful benefits for disease prevention, and there’s also evidence that they can help prevent weight gain.

Don’t narrow your mind down to the fact that the calories from whole grains, whole fruits, and vegetables disappear. What’s likely happening is that when people increase their intake of these foods, they cut back on calories from other foods. Fiber may be responsible for these foods’ weight control benefits, since fiber slows digestion, helping to curb hunger. Fruits and vegetables are also high in water, which may help people feel fuller on fewer calories.

 

• Nuts and Weight

 

“Nuts pack a lot of calories into a small package and are high in fat, so they were once considered taboo for dieters or even anyone who wants to stay healthy. But as we may have it, studies find that eating nuts does not lead to weight gain and may instead help with weight control, perhaps because nuts are rich in protein and fiber, both of which may help people feel fuller and less hungry. People who regularly eat nuts are less likely to have heart attacks or die from heart disease than those who rarely eat them, which is another reason to include nuts in a healthy diet. 

 

• Dairy and Weight

 

“The U.S. dairy industry has aggressively promoted the weight-loss benefits of milk and other dairy products, based largely on findings from short-term studies it has funded. But a recent review of nearly 50 randomized trials finds little evidence that high dairy or calcium intakes help with weight loss. Similarly, most long-term follow-up studies have not found that dairy or calcium protect against weight gain, and one study in adolescents found high milk intakes to be associated with increased body mass index. 

One exception is the recent dietary and lifestyle change study from the Harvard School of Public Health, which found that people who increased their yogurt intake gained less weight; increases in milk and cheese intake, however, did not appear to promote weight loss or gain. It’s possible that the beneficial bacteria in yogurt may influence weight control, but more research is needed.

Yoghurt tends to keep the gut health at check and easily filling with less calorie, it could proffer solutions to the weight loss saga.

 

• Sugar-Sweetened Beverages and Weight

 

There’s convincing evidence that sugary drinks increase the risk of weight gain, obesity, and diabetes:  A systematic review and meta-analysis of 88 studies found “clear associations of soft drink intake with increased caloric intake and body weight.”  In children and adolescents, a more recent meta analysis estimates that for every additional 12-ounce serving of sugary beverage consumed each day, body mass index increases by 0.08 units.  Another meta analysis finds that adults who regularly drink sugary beverages have a 26 percent higher risk of developing type 2 diabetes than people who rarely drink sugary beverages.  Emerging evidence also suggests that high sugary beverage intake increases the risk of heart disease. 

Like refined grains and potatoes, sugary beverages are high in rapidly-digested carbohydrates. Research suggests that when that carbohydrate is delivered in liquid form, rather than solid form, it is not as satiating, and people don’t eat less to compensate for the extra calories. Liquid calories might tend to increase weight more than solid due to its low levels of satiety after consumption.

It really even seems that the number of overweight people had their fair share from sugary drinks than solid foods. A research conducted a while ago noticed that most overweight people really didn’t eat much solid foods but rather drank sugary drinks in their bottles.

 

• Fruit Juice and Weight

 

It’s important to note that fruit juices are not a better option for weight control than sugar-sweetened beverages ( who even suggested that?). Ounce for ounce, fruit juices-even those that are 100 percent fruit juice, with no added sugar- are as high in sugar and calories as sugary sodas. So it’s no surprise that a recent Harvard School of Public Health study, which tracked the diet and lifestyle habits of 120,000 men and women for up to 20 years, found that people who increased their intake of fruit juice gained more weight over time than people who did not. Pediatricians and public health advocates recommend that children and adults limit fruit juice to just a small glass a day, if they consume it at all.

It’s better to take fruits in their fresh form than their processed and packaged form.

 

• Alcohol and Weight

 

Even though most alcoholic beverages have more calories per ounce than sugar-sweetened beverages, there’s no clear-cut evidence that moderate drinking contributes to weight gain. It probably would lead to a protruded tummy because of the fact that the liver metabolizes it first after a meal and stores visceral fat during the process. While the recent diet and lifestyle change study found that people who increased their alcohol intake gained more weight over time, the findings varied by type of alcohol.  In most previous prospective studies, there was no difference in weight gain over time between light-to-moderate drinkers and nondrinkers, or the light-to-moderate drinkers gained less weight than nondrinkers. If you’ve seen heavy alcoholics in Nigeria, they’re actually lanky and look like a bag of bones. 

Breakfast, Meal Frequency, Snacking, and Weight

There is some evidence that skipping breakfast increases the risk of weight gain and obesity, though the evidence is stronger in children, especially teens, than it is in adults. Meal frequency and snacking have increased over the past years globally. -on average, children and most teen-adults get 27 percent of their daily calories from snacks, primarily from desserts and sugary drinks, and increasingly from salty snacks and candy. But there have been conflicting findings on the relationship between meal frequency, snacking, and weight control, and more research is needed.

Portion Sizes and Weight

“Since the 1970s, portion sizes have increased both for food eaten at home and for food eaten away from home, in adults and children. Short-term studies clearly demonstrate that when people are served larger portions, they eat more. There is an intuitive appeal to the idea that portion sizes increase obesity, but long-term prospective studies would help to strengthen this hypothesis.

Fast Food and Weight

Fast food is known for its large portions, low prices, high palatability, high sugar content, high fat content, reheating oil and high monosodium glutamate content; and there’s evidence from studies in teens and adults that frequent fast-food consumption contributes to overeating and weight gain. 

It’s really important to focus on home cooked meals than the ones from fast foods

 

The Bottom Line: Healthy Diet and Lifestyle Can Prevent Weight Gain and Chronic Disease

Weight gain in adulthood is often gradual, about a pound a year -too slow of a gain for most people to notice, but one that can add up, over time, to a weighty personal and public health problem. There’s increasing evidence that the same healthful food choices and diet patterns that help prevent heart disease, diabetes, and other chronic conditions may also help to prevent weight gain:

Choose minimally processed, whole foods-whole grains, vegetables, fruits, nuts, healthful sources of protein (fish, poultry, beans), and plant oils.

Limit sugar beverages, refined grains, potatoes, red and processed meats, and other highly processed foods, such as fast food.

Though the contribution of any one diet change to weight control may be small, together, the changes could add up to a considerable effect, over time and across the whole society. Since people’s food choices are shaped by their surroundings, it’s imperative for governments to promote policy and environmental changes that make healthy foods more accessible and decrease the availability and marketing of unhealthful foods.

 

Source: https://www.hsph.harvard.edu/obesity-prevention-source/obesity-causes/diet-and-weight/#:~:text=Choose%20minimally%20processed%2C%20whole%20foods,foods%2C%20such%20as%20fast%20food.

 

GASTROPARESIS

As a saying goes thus : “ to eat is human, to digest is divine; a number of people find it difficult to utilize their digestive tracts after enjoying a sumptuous meal. Really, it’s saddening to be afraid to eat that very delicious meal because you know you would probably be bloated or even constipated. So, what to do? 

Let’s take a look at this exciting digestive disorder called gastroparesis, shall we?

Gastroparesis (abbreviated as GP) represents a clinical syndrome characterized by sluggish emptying of solid food (and more rarely, liquid nutrients) from the stomach, which causes persistent digestive symptoms especially nausea and primarily affects young to middle-aged women, but is also known to affect younger children and males.

It’s thought to be the result of a problem with the nerves (vagus) and muscles that control how the stomach empties.

Sadly, If these nerves are damaged, the muscles of your stomach might become dysfunctional and the motility of food can slow down.

“While delayed emptying of the stomach is the clinical feature of gastroparesis, the relationship between the degree of delay in emptying and the intensity of digestive symptoms does not always match”. For instance, some diabetics may exhibit pronounced gastric stasis yet suffer very little from the classical gastroparetic symptoms of: nausea, vomiting, reflux, abdominal pain, bloating, fullness, and loss of appetite. “Rather, erratic blood-glucose control and life-threatening hypoglycemic episodes may be the only indication of diabetic gastroparesis. In another subset of patients (diabetic and non-diabetic) who suffer from disabling nausea that is to the degree that their ability to eat, sleep or carry out activities of daily living is disrupted gastric emptying may be normal, near normal, or intermittently delayed”. In such cases, a gastric neuro-electrical dysfunction, or gastric dysrhythmia (commonly found associated with gastroparesis syndrome), may be at fault.

 

DIABETES AND GASTROPARESIS 

Over time, diabetes can affect many parts of your body (especially nerves). One of those is the vagus nerve, which controls how quickly your stomach empties. “When it’s damaged, your digestion slows down and food stays in your body longer than it should”.

Although it’s more common in people with type 1 diabetes, people with type 2 can also get it.

 

From a study carried out by Phillips LK et al., 2015 : 

Glucose and gastric emptying: bidirectional relationship. The rate of gastric emptying is a critical determinant of postprandial glycemia. Glucose entry into the small intestine induces a feedback loop via CCK, peptide YY (PYY) and glucagon-like peptide 1 (GLP-1), which are secreted from the intestine in response to nutrient exposure. GLP-1 and gastric inhibitory polypeptide (GIP) induce the release of insulin, and GLP-1 inhibits glucagon secretion, which attenuates postprandial glycemic excursions. Amylin, which is co-secreted with insulin, also slows gastric emptying. At the same time, the blood glucose concentration modulates gastric emptying, such that acute elevations of blood glucose levels slow gastric emptying (effects are evident even within the physiological range) and emptying is accelerated during hypoglycemia.

 

DIAGNOSIS 

Diagnosis of gastroparesis begins with a doctor asking about symptoms and past medical and health experiences (history), and then performing a physical exam. Any medications that are being taken need to be disclosed.

Tests will likely be performed as part of the examination. These help to identify or rule out other conditions that might be causing symptoms. Tests also check for anything that may be blocking or obstructing stomach emptying. Examples of these tests include:

• a blood test,
• an upper endoscopy, which uses a flexible scope to look into the stomach,
• an upper GI series that looks at the stomach on an x-ray, or
• an ultrasound, which uses sound waves that create images to look for disease in the pancreas or gallbladder that may be causing symptoms.

 

SYMPTOMS 

The digestive symptom profile of nausea, vomiting, abdominal pain, reflux, bloating, early satiety, and anorexia can vary in patients both in combination and severity.

Others may include weight loss/weight gain, constipation and/or diarrhea, wide glycemic fluctuations in diabetics, belching and bloating-again, developing soon after meal ingestion and lasting for hours-along with visible abdominal distention. The distention and bloating may push up against the diaphragm making breathing uncomfortable.

“A poorly emptying stomach additionally predisposes patients to regurgitation of solid food, as well as gastroesophageal reflux disease (GERD)”. The reflux may range from mild through to severe. GERD complications can create esophageal spasm (also called non-cardiac chest pain) and can add to the burden of chronic pain. In severe cases, reflux aspiration pneumonitis compounds the clinical picture.

 

CAUSES

Reports from one tertiary referral center found that out of their 146 patients with gastroparesis: 36% were idiopathic (unknown causes), 29% were diabetic, 13% were post-surgical, 7.5% had Parkinson’s disease and 4.8% had collagen diseases. Any disease of metabolic, neurological (psychiatric, brainstem, autonomic including sympathetic and parasympathetic or enteric), or connective tissue (autoimmune) origin has the potential to disrupt gastric neural circuitry.

Apparently, diabetes is the most common known cause of gastroparesis. It can damage nerves — including the vagus nerve, which regulates your digestive system — and certain cells in your stomach.

Other causes of gastroparesis include:

• Injury to your vagus nerve from surgery
• A lack of thyroid hormone (hypothyroidism)
• Viral stomach infections (gastroenteritis)
• Medications such as narcotics and some antidepressants
• Parkinson’s disease
• Multiple sclerosis
• Rare conditions such as amyloidosis (deposits of protein fibers in tissues and organs) and scleroderma (a connective tissue disorder that affects your skin, blood vessels, skeletal muscles, and internal organs).

Related Disorders

A stomach motor disturbance known as “dumping syndrome” whereby food or liquids empty too quickly from the stomach can present with similar symptoms as are found in gastroparesis. Other disorders that may clinically present as gastroparesis (gastritis, gastric ulcers, pyloric stenosis, celiac disease, and GI obstructions) need to be ruled out.

 

TREATMENT 

You may find these tips helpful:

• instead of 3 meals a day, try smaller, more frequent meals – this means there’s less food in your stomach and it will be easier to pass through your system
• try soft and liquid foods, or even semi solid foods which are easier to digest. In severe cases, broths might be advisable. 
• Masticate well before swallowing ( i tried to check how long it’ll take to carefully grind a spoon of rice and i got 21seconds; you should try eating slowly. winks).
• drink non-fizzy liquids with each meal

It may also help to avoid certain foods that are hard to digest, such as apples with their skin on or high-fibre foods like oranges and broccoli, plus foods that are high in fat, which can also slow down digestion.

 

MEDICATIONS 

Use of drugs like domperidone, erythromycin, anti-emetics. Also note that these drugs might have side effects so it’s important to discuss with your doctor before using them. 

Domperidone should only be taken at the lowest effective dose for the shortest possible time because of the small risk of potentially serious heart-related side effects.

Other options like electric stimulation, botulinum toxin injections, a feeding tube, surgery

 

FOOTNOTE FOR DIABETICS

The nerves to the stomach can be damaged by high levels of blood glucose, so it’s important to keep your blood glucose levels under control if you have diabetes.

Your doctor alongside a dietitian can advise you about any changes you may need to make to your diet or medicine. For example, if you’re taking insulin, you may need to divide your dose before and after meals and inject insulin into areas where absorption is typically slower, such as into your thigh.

 

SOURCES: https://www.nhs.uk/conditions/gastroparesis/

https://rarediseases.org/rare-diseases/gastroparesis/

https://aboutgastroparesis.org/signs-symptoms.html/diagnosis-tests.html

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028327/

https://www.webmd.com/diabetes/type-1-diabetes-guide/diabetes-and-gastroparesis#1

 

Have you ever had a disruption in your bowels after taking a food you knew you shouldn’t have? 

That same way your face stays all day trying to live with the pain and discomfort is the same way your system feels when there is acidosis.

Metabolic acidosis happens when the chemical balance of acids and bases in your blood goes haywire. Most times, it might happen that your body:

• Is making too much acid
• Isn’t getting rid of enough acid
• Doesn’t have enough base to offset a normal amount of acid

When any of these happen, chemical reactions and processes in your body don’t work right.

Although severe episodes can be life-threatening, sometimes metabolic acidosis is a mild condition. You can treat it, but how depends on what’s causing it.

Causes of Metabolic Acidosis

Different things can set up an acid-base imbalance in your blood

Ketoacidosis: When you have diabetes and don’t get enough insulin and get dehydrated, your body burns fat instead of carbs as fuel, and that makes ketones. Lots of ketones in your blood turn it acidic. People who drink a lot of alcohol for a long time and don’t eat enough also build up ketones. It can happen when you aren’t eating at all, too. Also, a prolonged keto diet could lead to build up of ketones if not supervised well; especially if it’s for the wrong purposes. 

Lactic acidosis: Lactic acid build up occurs when there is enough oxygen in the muscles to breakdown glycogen and glucose . This acid can build up, too. It might happen when you’reexercising intensely. Big drops in blood pressure, heart failure, cardiac arrest, and an overwhelming infection can also cause it.

Renal tubular acidosis:  This medical condition happens when there is accumulation of acid in the body due to the kidney’s failure to appropriately acidify urine. Healthy kidneys take acids out of your blood and get rid of them

Have you ever had a disruption in your bowels after taking a food you knew you shouldn’t have? 

That same way your face stays all day trying to live with the pain and discomfort is the same way your system feels when there is acidosis.

Metabolic acidosis happens when the chemical balance of acids and bases in your blood goes haywire. Most times, it might happen that your body:

• Is making too much acid
• Isn’t getting rid of enough acid
• Doesn’t have enough base to offset a normal amount of acid

When any of these happen, chemical reactions and processes in your body don’t work right.

Although severe episodes can be life-threatening, sometimes metabolic acidosis is a mild condition. You can treat it, but how depends on what’s causing it.

Causes of Metabolic Acidosis

Different things can set up an acid-base imbalance in your blood

Ketoacidosis: When you have diabetes and don’t get enough insulin and get dehydrated, your body burns fat instead of carbs as fuel, and that makes ketones. Lots of ketones in your blood turn it acidic. People who drink a lot of alcohol for a long time and don’t eat enough also build up ketones. It can happen when you aren’t eating at all, too. Also, a prolonged keto diet could lead to build up of ketones if not supervised well; especially if it’s for the wrong purposes. 

Lactic acidosis: Lactic acid build up occurs when there is enough oxygen in the muscles to breakdown glycogen and glucose . This acid can build up, too. It might happen when you’re exercising intensely. Big drops in blood prrssure,  heart failure, cardiac arrest, and an overwhelming infection can also cause it.

 

Renal tubular acidosis:  This medical condition happens when there is accumulation of acid in the body due to the kidney’s failure to appropriately acidify urine. Healthy kidneys take acids out of your blood and get rid of them in your pee. Kidney diseases as well as some immune system and genetic disorders can damage kidneys so they leave too much acid in your blood.

Hyperchloremic acidosis. Severe diarrhea, laxative abuse, and kidney problems can cause lower levels of bicarbonate, the base that helps neutralize acids in blood.

Respiratory acidosis also results in blood that’s too acidic. But it starts in a different way, when your body has too much carbon dioxide because of a problem with your lungs.

Symptoms

Although symptoms can differ, someone with metabolic acidosis will often:

• Breathe fast
• Have a fast heartbeat
• Have a headache
• Be confused
• Feel weak
• Feel tired
• Have little desire to eat
• Feel sick to their stomach
• Throw up

Fruity-smelling breath (kasmaul breathing)is a classic symptom of diabetic ketoacidosis (DKA).

If you have these symptoms, call your doctor or visit the hospital immediately.  

Testing

Tests like anion gap, arterial blood gases and urine tests could help figure out if any of these acidosis occurs.

 

Prevention

You can’t always prevent metabolic acidosis, but there are things you can do to lessen the chance of it happening.

Drink plenty of water and non-alcoholic fluids. Your pee should be clear or pale yellow.

Limit alcohol. It can increase acid buildup. It can also dehydrate you.

Manage your diabetes, make sure you adhere to drug use by physician and also diet regimen by dietitian.

Follow directions strictly when you take your medications and do not self medicate no matter how small and familiar the symptoms might be.

 

Treatment

You treat metabolic acidosis by treating what’s causing it. If you don’t restore the balance, it can affect your bones, muscles, and kidneys. In severe cases, it can cause shock or death. DKA can put you in a coma.

The earlier you’re treated, the better. Common treatments include:

• Detoxification, if you have drug or alcohol poisoning
• Insulin, if you have DKA
• IV fluids, given by needle through a vein in your arm
• Sodium bicarbonate, by IV

You might have to go to a hospital.
your pee. Kidney diseases as well as some immune system and genetic disorders can damage kidneys so they leave too much acid in your blood.

Hyperchloremic acidosis. Severe diarrhea, laxative abuse, and kidney problems can cause lower levels of bicarbonate, the base that helps neutralize acids in blood.

Respiratory acidosis also results in blood that’s too acidic. But it starts in a different way, when your body has too much carbondioxide  because of a problem with your lungs.

Symptoms

Although symptoms can differ, someone with metabolic acidosis will often:

• Breathe fast
• Have a fast heartbeat
• Have a headache
• Be confused
• Feel weak
• Feel tired
• Have little desire to eat
• Feel sick to their stomach
• Throw up

Fruity-smelling breath (kasmaul breathing)is a classic symptom of diabetic ketoacidosis (DKA).

If you have these symptoms, call your doctor or visit the hospital immediately.  

Testing

Tests like anion gap, arterial blood gases and urine tests could help figure out if any of these acidosis occurs.

Prevention

You can’t always prevent metabolic acidosis, but there are things you can do to lessen the chance of it happening.

Drink plenty of water and non-alcoholic drinks, avoid fizzy drinks. Your pee should be clear or pale yellow.

Limit alcohol. It can increase acid buildup. It can also dehydrate you.

Manage your diabetes, make sure you adhere to drug use by physician and also diet regimen by dietitian.

Follow directions strictly when you take your medications and do not self medicate no matter how small and familiar the symptoms might be.

 

Treatment

You treat metabolic acidosis by treating what’s causing it. If you don’t restore the balance, it can affect your bones, muscles, and kidneys. In severe cases, it can cause shock or death. DKA can put you in a coma.

The earlier you’re treated, the better. Common treatments include:

• Detoxification, if you have drug or alcohol poisoning
• Insulin, if you have DKA
• IV fluids, given by needle through a vein in your arm
• Sodium bicarbonate, by IV

You might have to go to a hospital.